Musculoskeletal Disorders (MSDS) continues as one of the biggest health and safety issues throughout the world. One reason for this situation is that risk management practices at work are currently failing to meet several important evidence-based requirements for effective MSD risk reduction. In particular: they have mostly failed to overcome the risks arising from psychosocial hazards; Don’t let adequate participation by workers; And often fail to control the risk of the source.

To overcome this deficiency, the participatory hazard identification tool (Ahirm) has been formulated in accordance with the two frameworks developed by the principles of world health and science science. It consists of a set of online tools that include automatic data analysis and reporting modules, and procedures for guiding users through five conventional risk management cycles. Important, this assesses the level of danger and risk for groups of people who do certain jobs, focusing on overall work than only on tasks that are considered dangerous.

The intended user is the workplace manager and consultant responsible for the health and safety of work, with active participation as well as workers. Resulted risk control interventions are adjusted to overcome the main physical and psychosocial hazards identified for target work, and repetition of risk management cycles allow evaluation of sustainable results in terms of danger and risk.

Identification of gender differences in factors that influence the shoulder, neck and top of the MSD limb using the Multivariate Adaptive Regression Splines (Mars).

In this study, the model based on the multivariate adaptive regression splines (Mars) was proposed to study gender influences in factors that influence the development of shoulder, neck and legs over MSD. Two different Mars models, according to men and women, are built to identify variables with the strongest effects on MSD targets. Both models are able to predict the success of the occurrence of disorders learned.

Men seem to be more susceptible to physical risk factors and some other working conditions, while women seem to be more affected by psychosocial risk factors and activities carried out outside their working hours. According to the results, gender needs to be considered to ensure the success and effectiveness of ergonomic intervention in all worker populations.

Exploring CPGs is specialized in diseases in the human male genital abnormality using MSD-AFLP.

The incidence of male reproductive system disorders, especially hypospadia, has increased in developed countries since the second half of the 20th century. Chemicals that disrupt endocrine from the environment are considered involved in hypospadia onset through epigenetic changes. This pilot study aims to explore the CPG specific methylation of the disease in the patient’s sample exhibited with metyl). We compare clinical samples from hypospadia and phimosis patients.

Blood foreskin and sample were collected from patients one to two years with hypospadia (n = 3) and phimosis (n = 3) during surgical care. MSD-AFLP analysis shows a significant decrease in CPG methylation gene levels such as MyH11 and an increase in the level of CPG methylation gene such as PLA2G15 in hypospadia patients. Analysis of hierarchical grouping shows that genes with CPG levels that change significantly are significantly changed in DNA from the blood than from the skin of the earth. Because a small number of samples, further investigations are needed to explain the relationship between variations on CPG levels on bloodshed and blood DNA and male genital abnormalities.

In the MSD-ѱ generation of HIV provincial classes damaged.

Antiretroviral therapy (ART) can effectively reduce sustainable HIV replication and block the development of the disease, but infections have never been cured due to the persistence of small collection of infected cells with latent, provirus HIV competent replication. However, most of the HIV provirus in patients treated with art is incompetent replication because of various genetic defects. Most of the provirus damaged (around 90%) contains large internal removal or G-to-A hypermutation, produces most destruction if not all viral open reading frames, which are consistent with the idea that cytotoxic cell (CTLS) removes cells effectively , which produces viral antigens.

The interesting subclass of the disabled provirus (around 10%) which is consistently detected in these patients brings small removal or mutation of points in a relatively right area and is preserved near 5 ‘HIV genome tip, in the area that encodes the Major Splice Donor site (MSD ) And the packaging signal ѱ in the virus RNA genome. Why this subceRim provirus is damaged it has never been well understood. We now propose a mechanistic scenario for how MSD-ѱ mutations can prevent viral protein expressions. Based on sufficient results in the literature, we argue that MSD’s inactivation triggers the activities of 5’-polyiadenilation sites, resulting in production of Ultra-short non-protein-coding HIV transcripts.

Measurement of IL-21 in serum and human plasma use the ultrasensitive methodology of MSD S-Plex® and Quantierix Simoa.

IL-21 is a pleiotropic cytokine that plays a key role in modulating inflammatory responses, including autoimmune disease promotion. Some groups have reached the level of IL-21 circuits in plasma and serum samples using various commercial elisa. We are determined, however, that the most commonly used commercial tests in published literature are not specific or sensitive to detect IL-21 levels in heparin plasma or serum from healthy human individuals. These findings encourage efforts to develop more specific and sensitive methods to measure IL-21 in a complex biological matrix using anti-IL-21 antibodies belonging to the Quantierix Simoa platform and the S-Plex® S-Plex® Meso S-PLEX® format (MSD).

Anti-Hu CD16 Alexa Fluor® 488
A4-646-T100	ExBio	100 tests	EUR 269

Goat anti Mouse IgG1 (Alexa Fluor 488)
43R-1649	Fitzgerald	500 ug	EUR 570
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

Anti-Hu CD72 Alexa Fluor® 488
A4-310-T100	ExBio	100 tests	EUR 269

Anti-Bov CD9 Alexa Fluor® 488
A4-354-C100	ExBio	0.1 mg	EUR 269

AF488-streptavidin conjugate [Streptavidin, Alexa Fluor™ 488 Conjugate]
16891	AAT Bioquest	1 mg	EUR 176

AF488 Phalloidin [equivalent to Alexa Fluor® 488 phalloidin]
23153	AAT Bioquest	300 Tests	EUR 306

Endoglin/CD105 Alexa Fluor
FC15024	Neuromics	100 Tests	EUR 448

Goat Anti-Mouse IgG(H+L) Alexa Fluor 488–conjugated
S0017	Affbiotech	200ul	EUR 304

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 488–conjugated
S0018	Affbiotech	200ul	EUR 304

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 488
A4-686-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 488
A4-712-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 488
A4-730-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 488
A4-737-C100	ExBio	0.1 mg	EUR 269

Donkey Anti-Rabbit IgG (H+L), Alexa Fluor® 488 Conjugated
Ab8032-001	GenDepot	0.5mg	EUR 435

SAM FCM (Alexa Fluor 647)
abx098902-100tests	Abbexa	100 tests	EUR 1233

Anti-LAMP3 (human) Monoclonal Antibody (104G4) (Alexa Fluor® 488)
M09406	BosterBio	100ug	EUR 565
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Alpha Fluor™ 488 amine
1705	AAT Bioquest	1 mg	EUR 306

Alpha Fluor™ 488 Hydroxylamine
1900	AAT Bioquest	1 mg	EUR 306

Anti-LAMP3 antibody (Alexa-fluor 546)
STJ170005	St John's Laboratory	100 µg	EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-LAMP3 antibody (Alexa-fluor 647)
STJ170006	St John's Laboratory	100 µg	EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-IL3RA antibody (Alexa-fluor 546)
STJ170010	St John's Laboratory	100 µg	EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 647)
STJ170011	St John's Laboratory	100 µg	EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-CD207 antibody (Alexa-fluor 546)
STJ170015	St John's Laboratory	100 µg	EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 647)
STJ170016	St John's Laboratory	100 µg	EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-IL7R antibody (Alexa-fluor 546)
STJ170021	St John's Laboratory	100 µg	EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 647)
STJ170022	St John's Laboratory	100 µg	EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-Langerin (human) Monoclonal Antibody (DCGM4/122D5) (Alexa Fluor® 488)
M02316	BosterBio	100ug	EUR 580
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Alpha Fluor™ 488 NHS Ester
1812	AAT Bioquest	1 mg	EUR 219

Streptavidin-Alexa488 (Alexas fluor 488) conjugate
SV-A488-100	Alpha Diagnostics	100 tests	EUR 225

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)
50336	Alpha Diagnostics	0.5 ml	EUR 225

Alpha Fluor™ 532 acid [equivalent to Alexa Fluor™ 532 acid]
1795	AAT Bioquest	10 mg	EUR 393

Mouse IgG1-Alexa 488 conjugate (isotype control)
20102-101-A488	Alpha Diagnostics	50 Tests	EUR 263

Anti-Hu CD30 Alexa Fluor® 700
A7-455-T100	ExBio	100 tests	EUR 269

Anti-Hu CD94 Alexa Fluor® 700
A7-727-T100	ExBio	100 tests	EUR 269

Anti-Hu CD56 Alexa Fluor® 700
A7-789-T100	ExBio	100 tests	EUR 269

AF350-streptavidin conjugate [Streptavidin, Alexa Fluor™ 350 Conjugate]
16890	AAT Bioquest	1 mg	EUR 176

AF594-streptavidin conjugate [Streptavidin, Alexa Fluor™ 594 Conjugate]
16892	AAT Bioquest	1 mg	EUR 176

AF350 Phalloidin [equivalent to Alexa Fluor® 350 phalloidin]
23150	AAT Bioquest	300 Tests	EUR 306

AF594 Phalloidin [equivalent to Alexa Fluor® 594 phalloidin]
23158	AAT Bioquest	300 Tests	EUR 306

Donkey anti Goat IgG (H + L) (Alexa Fluor 594)
43R-ID005AF	Fitzgerald	500 ug	EUR 338
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)
43R-ID022AF	Fitzgerald	500 ug	EUR 364
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Goat IgG (H + L) (Alexa Fluor 647)
43R-ID028AF	Fitzgerald	500 ug	EUR 430
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)
43R-ID047AF	Fitzgerald	500 ug	EUR 462
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 594)
43R-ID056AF	Fitzgerald	500 ug	EUR 343
Description: Donkey anti Chicken IgY secondary antibody (H + L) (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 647)
43R-ID060AF	Fitzgerald	300 ug	EUR 425
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647)

Rabbit anti Chicken IgY (H + L) (Alexa Fluor 594)
43R-IR016AF	Fitzgerald	1 mg	EUR 281
Description: Rabbit anti Chicken IgY (H + L) secondary antibody (Alexa Fluor 594)

Goat Anti-Mouse IgG(H+L) Alexa Fluor 594–conjugated
S0005	Affbiotech	200ul	EUR 376

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 594–conjugated
S0006	Affbiotech	200ul	EUR 376

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 647–conjugated
S0013	Affbiotech	200ul	EUR 304

Goat Anti-Mouse IgG(H+L) Alexa Fluor 647–conjugated
S0014	Affbiotech	200ul	EUR 304

Mouse pre-microRNA Expression Construct mir-488
MMIR-488-PA-1	SBI	Bacterial Streak	EUR 684

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647
A6-686-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 647
A6-712-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647
A6-730-C100	ExBio	0.1 mg	EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647
A6-737-C100	ExBio	0.1 mg	EUR 269

Donkey Anti-Goat IgG (H+L), Alexa Fluor® 594 Conjugated
Ab8011-001	GenDepot	1mg	EUR 334

Donkey anti Goat IgG (H + L) (Fab 2) (Alexa Fluor 594)
43R-ID012AF	Fitzgerald	300 ug	EUR 410
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594)

Rabbit Anti-Rat IgG (H+L)-Alexa 594 Fluor conjugate (adsorbed with human IgG)
50337	Alpha Diagnostics	0.5 ml	EUR 225

Tide Fluor 2-LL-37
H-8286.0100	Bachem	0.1mg	EUR 312
Description: Sum Formula: C205H340N60O53+dye

Tide Fluor 2-LL-37
H-8286.0500	Bachem	0.5mg	EUR 1017
Description: Sum Formula: C205H340N60O53+dye

Anti-Cytokeratins Alexa Fluor488
A4-108-C025	ExBio	0.025 mg	EUR 175

Anti-Cytokeratins Alexa Fluor488
A4-108-C100	ExBio	0.1 mg	EUR 310

Anti-PSMA Alexa Fluor488
A4-539-C025	ExBio	0.025 mg	EUR 227

Anti-PSMA Alexa Fluor488
A4-539-C100	ExBio	0.1 mg	EUR 414

Anti-FoxP3 Alexa Fluor488
A4-601-C025	ExBio	0.025 mg	EUR 201

Anti-FoxP3 Alexa Fluor488
A4-601-C100	ExBio	0.1 mg	EUR 362

Anti-Phosphotyrosine Alexa Fluor647
A6-263-C025	ExBio	0.025 mg	EUR 154

Anti-Phosphotyrosine Alexa Fluor647
A6-263-C100	ExBio	0.1 mg	EUR 269

Anti-LCK Alexa Fluor647
A6-269-C025	ExBio	0.025 mg	EUR 206

Anti-LCK Alexa Fluor647
A6-269-C100	ExBio	0.1 mg	EUR 373

Anti-FoxP3 Alexa Fluor647
A6-601-C025	ExBio	0.025 mg	EUR 201

Anti-FoxP3 Alexa Fluor647
A6-601-C100	ExBio	0.1 mg	EUR 362

Recombinant (E.Coli) Hepatitis C Virus (HCV) NS5 Genotype-2a
RP-488	Alpha Diagnostics	100 ug	EUR 286

4-1BB Ligand / TNFSF9 Recombinant Protein
11-488	ProSci	0.1 mg	EUR 595.25
Description: Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

IL-6R Recombinant Protein
90-488	ProSci	50 ug	EUR 516.5
Description: Interleukin 6 receptor (IL-6R; CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.

Serpin F1 Recombinant Protein
91-488	ProSci	0.05 mg	EUR 542.75
Description: Serpin F1 is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. Serpin F1 is a new promising approach for the treatment of osteosarcoma and has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Levels of the natural ocular anti-angiogenic factor SentrinF1 (PEDF) is associated with proliferative retinopathy.

HVEM Recombinant Protein
92-488	ProSci	0.05 mg	EUR 311.75
Description: Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting state. Interaction of HVEM with TNF family member LIGHT co-stimulates T cells and promotes inflammation. HVEM also triggers inhibitory signaling cascade in effector T (Teff) cells and regulatory T cells (Tregs) as a ligand of B and T lymphocyte attenuator. Tnfrsf14 is detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. It has demonstrated that HVEM Ig is able to exert a significant antiviral effect against HSV-1 infection in vivo.

Monoclonal Anti-Monkey IgG-Alexa 488 Conj. (specific for monkey; no reactivity with human or animals IgG)
70030-AF488	Alpha Diagnostics	50 tests	EUR 347

CellBriteâ„¢ Fix 488
30090	Biotium	1KIT	EUR 644
Description: Minimum order quantity: 1 unit of 1KIT

Alpha Fluor™ 532 NHS Ester
1819	AAT Bioquest	1 mg	EUR 219

Alpha Fluor™ 594 C5 Maleimide
1891	AAT Bioquest	1 mg	EUR 219

Metal Fluor™ Zn-520, AM
21263	AAT Bioquest	1 mg	EUR 219

Helix Fluor™ 6-JOE Phosphoramidite
6046	AAT Bioquest	100 umoles	EUR 50

Streptavidin-Alexa594 (Alexas fluor 594) conjugate
SV-A594-100	Alpha Diagnostics	100 tests	EUR 225

Tide Fluor 2-LL-37 (scrambled)
H-8288.0100	Bachem	0.1mg	EUR 312
Description: Sum Formula: C205H340N60O53+dye

Tide Fluor 2-LL-37 (scrambled)
H-8288.0500	Bachem	0.5mg	EUR 1017
Description: Sum Formula: C205H340N60O53+dye

Tide Fluor 5WS-o-Conotoxin GVIA
H-8356.0100	Bachem	0.1mg	EUR 1146
Description: Sum Formula: C120H182N38O43S6+dye

Anti-Cytokeratin 18 Alexa Fluor488
A4-106-C025	ExBio	0.025 mg	EUR 186

Anti-Cytokeratin 18 Alexa Fluor488
A4-106-C100	ExBio	0.1 mg	EUR 331

Anti-Cytokeratin 19 Alexa Fluor488
A4-120-C025	ExBio	0.025 mg	EUR 186

Anti-Cytokeratin 19 Alexa Fluor488
A4-120-C100	ExBio	0.1 mg	EUR 331

Anti-Ki-67 Alexa Fluor488
A4-155-T025	ExBio	25 tests	EUR 154

The testing developed on both technology platforms was characterized in the plasma heparin and serum using a recovery of surge in various concentrations. Each method can detect sub-pg / ml IL-21 levels (Detection Prediction limit of [LOD] around 1.0 FG / mL for the QuantiX Simoa and MSD S-Plex® platform) which is 200-500 times lower than the current commercial test ,